Be Very Careful: If You Notice This Skin Growth, It Could Be Serious

The 5-Second Rule Dermatologists Use: ABCDE

If you only remember one thing from this article, make it this.

Dermatologists often use the ABCDE rule to help flag moles that deserve a closer look.

  • A — Asymmetry: One half doesn’t match the other.
  • B — Border: The edges look irregular, blurred, ragged, or “spreading.”
  • C — Color: Multiple shades appear in one spot (brown, black, red, white, blue, or gray).
  • D — Diameter: Larger spots can be higher-risk (especially if growing).
  • E — Evolving: Any noticeable change over time—size, shape, color, surface, or symptoms.

That last one is the big one.

Evolving is often what separates a harmless mole from something worth checking.

A stable mole that hasn’t changed for years is usually less concerning than a spot that suddenly looks “different.”

And “different” can be subtle.

A slightly rougher surface. A new darker streak. An edge that looks less clean than it used to.

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