September 3, 2026

Could These Common Medications Be Putting Extra Stress on Your Kidneys? 8 Drugs Worth Knowing About

However, understanding which medications may affect kidney health can help you have informed conversations with your doctor and use them safely.

Why Some Medications Affect the Kidneys

The kidneys filter large amounts of blood every day.

As medications pass through the body, the kidneys often help break them down or remove them.

Some drugs may:

  • Reduce blood flow to the kidneys
  • Cause inflammation
  • Affect kidney filtration
  • Increase the risk of kidney injury in susceptible individuals

The risk is often higher in:

  • Older adults
  • People with diabetes
  • Individuals with high blood pressure
  • Those with existing kidney disease
  • People taking multiple medications

1. Lithium

Lithium is commonly prescribed to help manage bipolar disorder.

While it can be highly effective, long-term use may affect kidney function in some individuals.

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