Weight loss Losing significant amount of weight due to no apparent reason is one of the signs of cancer in general, including pancreatic cancer. Digestive Problems Poor digestion, loose stools, or stools that are oily and are accompanied by a strong odor may be a result of interference with the pancreas’s enzyme production because of the presence of cancer. Bowel changes When and if the pancreatic duct blocks, it may result in a symptom called steatorrhoea or fatty stools. This means the body is not absorbing your food properly. Other bowel changes may include diarrhoea and constipation. New-Onset Diabetes In some cases, pancreatic cancer impacts insulin production, causing diabetes in people who were not diabetic before. Fatigue As with most other cancers, fatigue and lack of energy can be symptoms accompanying pancreatic cancer. Blood Clots The risk of developing blood clots increases when a person is diagnosed with pancreatic cancer. This is known as deep vein thrombosis (DVT).